我院成功开展HPV检测项目啦！
什么是HPV
人类乳头瘤病毒（ Humanpapillomavirus，简称HPV）是宫颈癌的主要病因，而其中，26－30岁和46－50岁是女性感染hpv的高峰期，持续感染hpv病毒且不做任何预防手段是宫颈癌发病的高危人群，根据世界卫生组织最新数据显示：宫颈癌的发病率在女性癌症中排名第二，仅次于乳腺癌，每年约有50万新增发病案例。在我国，女性宫颈癌的风险为0.9％左右，并且近年来愈加有上升和年轻化趋势。
HPV的分型
HPV一般可以分为160多种亚型，而亚型又分为两大种类型，可以分为低危型和高危型，低危型和高危型HPV病毒导致的疾病不同，致病性也有所不同。低危型HPV病毒往往导致的是生殖道尖锐湿疣的发生，常见的为6、11这两种类型。而高危型HPV病毒长期持续存在感染，可能会导致宫颈恶性病变，高危型HPV病毒的致病性也有所不同，其中16、18的致病性最强，可能会导致70%宫颈癌的发生，而在亚洲女性中31、33、52、58等类型的HPV感染也较常见。
HPV感染在宫颈癌自然史中的作用及感染过程
HPV感染生殖道是一个长期的过程，可潜伏在细胞内若干年，一旦机体免疫力降低，潜伏的病毒可恢复活动。HPV感染过程通常分为潜伏感染期、亚临床感染期、临床症状期和HPV相关的肿瘤期。
宫颈癌也有一系列的前驱病变，即宫颈上皮不典型增生，在病理上称宫颈上皮内瘤变（CIN），通常又根据严重程度分成三级：宮颈上皮内轻度瘤变（CINI）、宮颈上皮内中度瘤变（CINll）和宫颈上皮内高度瘤变（ CINlll）这些癌前病变均有可能发展为宫颈浸润癌。
等有了症状再去医院检查宫颈健康？
调查研究表明
治疗的癌前病变和宫颈癌
高达70%是没有任何临床症状的。
所以，筛查，很重要！
Hpv检查的临床意义
1.宫颈癌筛查
单独用于宫颈癌初筛和细胞学联合检测ASCUS的分流与管理
2.把潜在患子宫颈癌风险妇女从低风险妇女中分离出来，合理指导阴道镜的使用，提高诊断率，降低漏诊风险；
3.CIN转归的预测
若CIN不伴高危型HPV感染，预示良性转归
4.宫颈病变术后的追踪与管理
用于宫颈病变术后提示病灶是否清除干净，提示有残留病灶或复发可能
Hpv检查的适应症
1.宫颈癌的筛查应该从21岁以上的妇女开始，但已经开始性生活，而且处于性活跃状态的21岁以下的青年女性也应该定期进行宫颈癌的筛查。
2.21-29岁年龄段的妇女，应该每两年进行一次筛查。
3.30岁以上妇女，如果没有CIN 2 或者 CIN 3，不是艾滋病病毒感染者，不处于免疫抑制状态（例如免疫病或者器官移植后患者，需要长期服用免疫抑制剂），没有子宫内的DES暴露史（通常指，本人的母亲在妊娠期曾经接受过不适当的雌激素治疗病史），而且连续三次筛查结果都正常，可以将筛查的间隔改为每三年一次。
4.对于30岁以上的妇女，最佳的筛查方式是同时进行细胞学筛查（TCT）和宫颈HPV病毒检测，如果两项结果都正常，属于宫颈癌的低危人群，筛查的间隔可以在三年以上。
5.接种过HPV-16 和HPV-18疫苗的青少年，一旦开始了性生活，应该和未接种者一样，遵循以上的筛查指南。
6.男性或者女性患生殖器疣，应检测HPV病毒。
7.适用于皮肤疣的HPV检测。
现在宫颈癌筛查普遍使用的是宫颈液基细胞学检查和Hpv检查两种联合筛查。
宫颈癌是目前唯一病因明确，可以早发现、预防并有疫苗的癌症。
我院引进了先进的仪器设备，开展了HPV检测，可检测18种高危亚型及6种低危型，最快当天拿结果，填补了南溪区该项目检测的空白，为广大女性同胞带来福音！
温馨提示:1、当发现报告中HPV阳性也不要太紧张,但需要重视;
2、及时到医院进行治疗,遵医嘱;
生活中要增强体质,提高自身免疫力是预防及治疗宫颈HPV感染的最有效的方法。
撰稿人：王彬竹 编辑：曹芳
审核： 杨乾芳
深化全民医保制度重点改革---全面推广医保电子凭证工作
2021-04-12 下一篇南溪区全民免费接种新冠病毒疫苗启动仪式在我院召开
2021-04-02 FreeMarker template error (DEBUG mode; use RETHROW in production!): For "." left-hand operand: Expected a hash, but this has evaluated to a string (wrapper: f.t.SimpleScalar): ==> asx [in template "templates/www.scstyjryy.cn/zh_CN/pc/dqgzxq.html" at line 86, column 54] ---- FTL stack trace ("~" means nesting-related): - Failed at: #if asx.parent?? [in template "templates/www.scstyjryy.cn/zh_CN/pc/dqgzxq.html" at line 86, column 49] ---- Java stack trace (for programmers): ---- freemarker.core.NonHashException: [... Exception message was already printed; see it above ...] at freemarker.core.Dot._eval(Dot.java:48) at freemarker.core.Expression.eval(Expression.java:81) at freemarker.core.ExistsExpression._eval(ExistsExpression.java:49) at freemarker.core.Expression.eval(Expression.java:81) at freemarker.core.Expression.evalToBoolean(Expression.java:145) at freemarker.core.Expression.evalToBoolean(Expression.java:131) at freemarker.core.IfBlock.accept(IfBlock.java:49) at freemarker.core.Environment.visit(Environment.java:326) at freemarker.core.Environment.visit(Environment.java:332) at freemarker.core.Environment.process(Environment.java:305) at freemarker.template.Template.process(Template.java:378) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.processTemplate(FreeMarkerView.java:367) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.doRender(FreeMarkerView.java:284) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.renderMergedTemplateModel(FreeMarkerView.java:234) at org.springframework.web.servlet.view.AbstractTemplateView.renderMergedOutputModel(AbstractTemplateView.java:167) at org.springframework.web.servlet.view.AbstractView.render(AbstractView.java:303) at org.springframework.web.servlet.DispatcherServlet.render(DispatcherServlet.java:1282) at org.springframework.web.servlet.DispatcherServlet.processDispatchResult(DispatcherServlet.java:1037) at org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:980) at org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:897) at org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:970) at org.springframework.web.servlet.FrameworkServlet.doGet(FrameworkServlet.java:861) at javax.servlet.http.HttpServlet.service(HttpServlet.java:635) at org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:846) at javax.servlet.http.HttpServlet.service(HttpServlet.java:742) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:231) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.springframework.boot.web.filter.ApplicationContextHeaderFilter.doFilterInternal(ApplicationContextHeaderFilter.java:55) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.apache.shiro.web.servlet.AbstractShiroFilter.executeChain(AbstractShiroFilter.java:449) at org.apache.shiro.web.servlet.AbstractShiroFilter$1.call(AbstractShiroFilter.java:365) at org.apache.shiro.subject.support.SubjectCallable.doCall(SubjectCallable.java:90) at org.apache.shiro.subject.support.SubjectCallable.call(SubjectCallable.java:83) at org.apache.shiro.subject.support.DelegatingSubject.execute(DelegatingSubject.java:387) at org.apache.shiro.web.servlet.AbstractShiroFilter.doFilterInternal(AbstractShiroFilter.java:362) at org.apache.shiro.web.servlet.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:125) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.apache.shiro.web.servlet.AdviceFilter.executeChain(AdviceFilter.java:108) at org.apache.shiro.web.servlet.AdviceFilter.doFilterInternal(AdviceFilter.java:137) at org.apache.shiro.web.servlet.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:125) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at com.alibaba.druid.support.http.WebStatFilter.doFilter(WebStatFilter.java:123) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.springframework.boot.actuate.trace.WebRequestTraceFilter.doFilterInternal(WebRequestTraceFilter.java:110) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.tuckey.web.filters.urlrewrite.RuleChain.handleRewrite(RuleChain.java:176) at org.tuckey.web.filters.urlrewrite.RuleChain.doRules(RuleChain.java:145) at org.tuckey.web.filters.urlrewrite.UrlRewriter.processRequest(UrlRewriter.java:92) at org.tuckey.web.filters.urlrewrite.UrlRewriteFilter.doFilter(UrlRewriteFilter.java:389) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.springframework.web.filter.RequestContextFilter.doFilterInternal(RequestContextFilter.java:99) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.springframework.web.filter.HttpPutFormContentFilter.doFilterInternal(HttpPutFormContentFilter.java:105) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.springframework.web.filter.HiddenHttpMethodFilter.doFilterInternal(HiddenHttpMethodFilter.java:81) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:197) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.springframework.boot.actuate.autoconfigure.MetricsFilter.doFilterInternal(MetricsFilter.java:106) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:193) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:166) at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:198) at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:96) at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:478) at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:140) at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:80) at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:87) at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:342) at org.apache.coyote.http11.Http11Processor.service(Http11Processor.java:799) at org.apache.coyote.AbstractProcessorLight.process(AbstractProcessorLight.java:66) at org.apache.coyote.AbstractProtocol$ConnectionHandler.process(AbstractProtocol.java:861) at org.apache.tomcat.util.net.NioEndpoint$SocketProcessor.doRun(NioEndpoint.java:1455) at org.apache.tomcat.util.net.SocketProcessorBase.run(SocketProcessorBase.java:49) at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1149) at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:624) at org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61) at java.lang.Thread.run(Thread.java:748)
